I see. So, if I set up an intricate browser clean-room environment, and I assume that the Javascript verification system you come up with actually works, I can get some of the benefit of simply installing GPG and using POP mail.
You'd still have to vet your GPG install & mail client code. Also, it's not difficult to fork the code to create a client that doesn't use the browser at all. It just hasn't happened yet.
How do you know which public key belongs to the address? Key servers? Web-of-trust? Look it up on their homepage?
Scramble has an address -> pubkey resolution system which balances security with usability.
At least with Scramble you can create a secure USB stick to boot from with all of that preconfigured. Any solution that uses bare GPG still has severe usability problems.