Facebook will now start acting more and more like Twitter: "If you are building anything on our platform that we might want to build in the future, then you'll get thrown off the platform eventually."
It's really starting to feel this way. I think it's still ok for developers building apps/games that uses Facebook platform but for a platform or any startup with some sort of social graph might want to think twice about it.
Facebook is much more of a "platform" than Twitter is, however. Though, personally, I don't use FB for anything other than on-site IMs and some status updates.