I started programming python with webapp2 also, after coming from a php, java, and node.js background. I found it to be a bit more low-level and manual as far as frameworks are concerned, but I discovered that to be enjoyable. While it did force me to write a bit more scaffolding, request, and model/caching code I know that I have a MUCH deeper understanding of the frameworks works as a whole and communicates end-to-end. It might have forced me to do more work initially but I find now that I have a deep knowledge of the framework (not just it's APIs and methods) I am able to iterate faster and stretch and bend the framework to work outside of it's traditional modeling - very much unlike other similar frameworks I have worked with in PHP/node.js
Have you tried any web development with Django? Under some light, it may be helpful to develop an app using webapp2, but normally you want to abstract most of it away.
Django has done it very nicely. I encourage you to explore it for it may save you countless hours you may end up spending in future.
