There are massive downsides to any antibiotic. A single dose of a broad-spectrum antibiotic can permanently alter a kid's gut microbiome and make them more likely to develop a variety of mental health issues like depression

https://theconversation.com/how-childhood-infections-requiri...

https://www.scientificamerican.com/article/a-single-course-o...

Penicillin resistant bacteria?

As someone with a severe allergy, lots of downsides to me!