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Absolutely not. If your brain is molded in a stressful environment, it’ll optimize for reaction to and preemption of threats, with all the anti-social behavior that entails, rather than creativity, cooperation, high-level learning, and constructive pro-social behaviors.


Do you have any references to support this? What you and the person you responded to said both seem reasonable to some extent, but without evidence It's not clear to what extent they are true.

Relatedly, does "stress" have the same meaning in what you say and others are saying? It seems reasonable (though I have no evidence or related expertise) that the optimal level of stress is non-zero (for some definition of stress, to the extent that it can be quantified). Why wouldn't the optimal level of stress promote more pro-social, creative, cooprerative, etc. behaviour than sub-optimal stress levels?


I went down a rabbit hole about this while reading The Telomere Effect (recommended reading). The book goes into the good stress vs. bad stress paradigm and how it has a biological basis - literally at the RNA level. There’s a Goldilocks zone where, for example, the right amount of good stress actually increases your lifespan, and the lack thereof is actually bad for you. Of course bad stress is bad in any amount, with bigger consequences if you’re younger or, get this, in the womb. If a pregnant woman experiences a traumatic event or bad or chronic stress, that can result in lifelong issues for the kid. I don’t recall if the book went beyond RNA and into the neuroscience aspect or whether that was from further reading, but the neurological effects are significant too.

Update:

Harvard Medical School article: Understanding the stress response https://www.health.harvard.edu/staying-healthy/understanding...

Research on effect on neural circuits: https://jneurodevdisorders.biomedcentral.com/articles/10.118...

Harvard article on impact of early childhood adversity, including on brain: https://developingchild.harvard.edu/resources/inbrief-the-im...


All of this is talking about physiological changes, which are well known, not gene expression. Gene expression is entirely different than the repercussions of psychological trauma.


See the following study in Nature and scroll down to “Epigenetic reprogramming by ELS: the current landscape” -it gives an overview with citations and links included:https://www.nature.com/articles/s41398-022-02076-9

Telomere Effect also goes into epigenetic changes but isn’t solely focused on stress


Do I get to count as evidence? The stress they're talking about is clearly defined. It's ACE levels.

Before the age of 5 I was hospitalized for falling out of a moving truck and had an ace score of 9, after adoption at 5 I had an ace score of 6-7. I was regularly beaten over the head, yelled at, had food withheld--the whole 9 yards. Almost always related to academic performance because I already had ADHD and PTSD from before adoption.

I now am starting to realize that beyond being easily triggered due to PTSD, I can ONLY function cognitively if I am under stress. It's taken me a long time to figure out if what I'm dealing with is ADHD, PTSD, dissociation, or what--it's hard to pin down. I finally realized that I perform, socialize, play, create and cooperate better if I am angry, scared, worried I'll get fired, or various other social pressures that make people panic. I am useless otherwise. I have come to the conclusion that I am adrenaline deficient because my brain developed in a wash of adrenaline and learned to stay there.

In social situations I come across as aloof or disinterested, absent, withdrawn, and when I'm excited about something or seeking socialization I come across as confrontational, argumentative, or upset when I'm happy and joking. I mostly don't see a point in socializing when I am not perceived according to my internal experience.

The only time I've ever been normal and functional is the 6 months after my mom died, a time when most people are incapacitated due to the stress of grief.

I gotta say as an N=1, having early childhood stressors and head trauma have not exactly made me more pro-social, creative, cooperative, etc. To get that Optimal level of stress requires that I destroy my body with cortisol.


I'm sorry for the ordeals you've gone through in your life, but gene expression is entirely different than psychological trauma.


It’s not different, the two are tied. See my comments above, including my response to you related to epigenetic changes from stress.

The person you are responding to likely has notable epigenetic modifications that have lasted way past the initial negative environmental stimuli (in proportion to the trauma). It’s not a hopeless situation, there is literature on how to reverse and mitigate that, but it’s important to be aware of.


No. There's no proof that the gene activation differences that occur are negative. There's no proof that the gene activation differences are the cause of the psychological and behavioral differences seen by victims of trauma.


If you're old enough to be here, you've already seen all the evidence you need.

And not just humans. Pretty easy to tell if an animal has been mistreated. Kittens raised on the street, where they compete with each other for food, are nothing like those born and raised indoors.

Do you really need "hard science" for this kind of stuff?


I don't think it's unreasonable to ask for "hard science" on this. Just as you've provided an anecdote of "street kittens," I have personal anecdotes of children who grew up in abusive families who turned out to be very nice people. Of course, there may have been less visible setbacks in other parts of their development, but at the end of the day it's not a clear-and-cut A causes B to me.


You are right. It's not unreasonable to ask, however it wouldn't hurt to demonstrate some basic acknowledgement that things do seem to be strongly correlated. Even the biggest idiots understand the concept.

You are also right that not everyone (human or different animal) reacts the same. Some turn the other cheek, some will break your nose. The scars will always be there, though.


I've never seen any evidence that changes in gene expression are mostly negative. The entire point is gene expression, not that stress or trauma causes a person to behave differently afterwards. It's weird that people on this thread don't seem to understand this very important distinction.


Little is done in psychology or the social sciences to therapeutically resocialize people who have maladaptive traits.

It's all presumed to be one's 'personal responsibility' that they were victims of their own kind.

The onus belongs on society to provide healthy and stable environments for people.


Since ‘society’ flat out isn’t going to do that, and it isn’t clear it could even afford to do so (or how), what do you propose to be the next most practical option?


I'm not sure one exists. You can't force a life form to care about others of its kind, so our potential will be limited by that nature.

Society never cares about the damage it inflicts until it's time to start talking about outcomes and results, usually after a mass killing or some other major meltdown that ends in murder.

99% of those would be avoided if mankind practiced what it preached.


Having pulled the string all the way down on a number of issues you’re identifying - your expected outcome is false.

While society can shift things around a bit, none of these underlying issues are actually ‘solvable’ without far more serious consequences.

Our current thinking and attempt at solving some of the current ‘justice’ issues for instances seems to be precipitating an even larger and more destructive evil.

The reason why you can’t force an organism to care about another of its kind, for instance, has a plausible evolutionary reason that it would be foolhardy to ignore. That others of another organisms kind have an incentive to take advantage of any sort of mechanism to capture the other organism and make it work against its interests.

Selfishness is the only viable defense against out of control selfishness.

Prior solutions create new problems and new pain, precipitating new attempts at solutions which create new problems and new pain, ad infinitum.

The wheel will continue to turn.


So there's no real reason for unity and connection, huh?

Certainly seems that way. The world is led by sociopaths who would rather see dead homeless people than miss a profit goal.

As the wheel turns, people will remember who was, and wasn't, there when things were poor, and abandon them in their greatest hour of need.


Far from it!

You’re getting your lesson reversed.

If no one is strong, there is no one to help the weak.

If one gives all their strength, then they are too weak to help anyone including themselves.

If Ukraine gave in to Russia, for example, then there would be no Ukraine, and a stronger and hungrier Russia.

Weakness breeds predators.

Strength gives options and an ability to actually help others from a place that isn’t predatory. A place that can be win-win.

Never actually helping anyone of course makes new enemies, and isn’t helping anyone either.

It’s a balance.




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