Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

Dupixent rocks! If you ever get sick of infections, it sounds like JAK inhibitors have opened the door to daily-pill eczema treatments too.


> If you ever get sick of infections

I assume you meant "injections" :)

For the value that Dupixent provides for me (effectively infinite), I'd do just about anything. So the injections don't bother me at all.

Though injections do make international travel a bit more complicated. Daily-pill eczema treatments would definitely be more convenient in that respect!


Ha! Autocorrect got me, I did mean to say injections ^_^;;

Although tbh I have had several nasty infections from then-untreated eczema...


I was actually on Dupixent for a while and I was one of the non-responders, so my derm put me on a JAK inhibitor daily pill.

The convenience is offset by higher risk of side effects, though luckily I seem to have avoided those.

The pills really seem to be the solution for me.

My eczema had gotten pretty bad in recent years, and much of what you said resonates with me, though I don't think I ever got to the point of being effectively disabled.

My skin is like 90% smooth now with some last stubborn patches, but I'm hoping with time they and the residual scarring will start to disappear.


Sorry to hear you're a non-responder to Dupixent. But really glad you found a different pill that seems to work!

I use to worry that my body would someday stop responding to Dupixent, and my whole life would suddenly crash down around me. But luckily that hasn't happened yet, and with all the monoclonal antibodies in the pipelines, I'm actually confident medicine will be able to outpace my condition.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: