I know some of you are following this closely and I have some questions I haven't seen any proper answer. I am hoping one of you can shine some light.
How long will the mod-RNA express the spike proteins? (where is the actual 'protein expression'/time plot?)
The poly(A) tail isn't just A (which would give a mechanic answer to my first question?), there is also a 10-nucleotide linker (GCAΨAΨGACΨ). I wonder if this could be there to trigger some sort of self-amplification. Can someone point me to the relevant paper?
How long will the mod-RNA express the spike proteins? (where is the actual 'protein expression'/time plot?)
The poly(A) tail isn't just A (which would give a mechanic answer to my first question?), there is also a 10-nucleotide linker (GCAΨAΨGACΨ). I wonder if this could be there to trigger some sort of self-amplification. Can someone point me to the relevant paper?