It's rare to see something as mass market and expensive as a modern AAA open world game making a "statement" that isn't extremely watered down and tepid - there's just too much at stake. And a piece of media that's fully embedded in multinational corporate culture is unlikely to seriously challenge that culture either. You'll have to look to the indie space for that.

Blade Runner was provocative, but it was also a box office bomb. Both times. The aesthetics of cyberpunk have broad mass market appeal - that much is certain. Yet the more philosophical, political and artistic questions and themes that define the genre, maybe not so much.