Negate the operating environments that calculations are made in and the operating environments are not an issue, alright.
There definitely is a lot of bloat in the software world, but even large bioninformatics organizations have their own data-pipeline management teams to keep these issues in spec.
Operating systems might be slow. Applications might be slow. SaaS might be slow.
But computation is not slow, and if you care about speed, you do computation in a context where the aforementioned issues are not issues.