I'd say one of the biggest roadblocks to nuclear power right now is public opinion. Nobody wants one in their backyard because there's a lot of false information (and shows like Chernobyl don't help). Even though we're well into the safe area, showing that we're making them even safer might help sway public opinion to build one where it otherwise wouldn't have been at all, regardless of the multi-billion dollar cost and decade+ timetable.
But that's not the big roadblock to nuclear power. The main obstacle is that it's grossly uneconomic. Even in locations where the locals are nearly 100% for reactor, the reactors are not being built. The people controlling the money don't see them as good investments.