The reason I don't believe it is because I doubt it has drivers for the latest graphics cards and modern desktop environments such as Gnome/KDE. Is Ryzen even supported? What about sleep/suspend and resume? What's the story on package management? Can you run VirtualBox / VMWare on it?

People used to talk like that when someone suggested they switch from windows to linux. My my, how times have changed...

Yes, those things work. You'll want to select hardware that is well supported though for the best experience.