Income inequality, labor arbitrage, job loss to industrial automation, exponential increases in the surveillance state, healthcare cost increases, this list could go on indefinitely. Scientists and engineers intentions are largely moot as long as their inventions and innovations are consistently used to further concentrate wealth and power in the hands of a vanishingly small minority of the world population.
Don't get too nostalgic about the middle ages: the landed gentry who will own the AI/fully automated factories will occasionally require mechanical-turk-type work done by the serfs. Which side will you be on when your job gets automated?