FWIW, this domain posted mostly AI generated or otherwise falsified "proof" of "Israel's Massacre in Gaza" which were not rarely debunked as either not even in the area, "Gazawood" stories (a child supposedly killed in Israeli strikes appeared many times as different children and was proven to be an actor), and is largely funded by a shadowy entity with its roots in Qatar.
I am not a fan of domain name cessation or any kind of blocking access to data, but I'd imagine NameCheap did have a particularly high amount of complaints and legal inquiries (one comes to mind, where the site posted pictures of a Hamas hostage in a tunnel as "Israel starves teacher and forces him to dig his own grave" that is in litigation), that at some point beg the question if $5/year is worth it.
Gazawood. Brings back the momories of the Russian internet trolls circa 2015+ denigrating white helmets online with similar slurs and supporting Assadists in their mass slaughter of Syrian population.
You're in a fitting company with your creative vocobulary.
In any case, you're clearly just lying. This website (formerly TikTokGenocide.com, before the recent forced name change to genocide.live due to post-zionist tiktok aquisition trademark violation claim) never "posted mostly AI generated or otherwise falsified content". What it mostly did, was to categorize and archive content shared by people from Gaza online on social media, and to provide some context/archival notes on it. That's it.
It's not that different from various Syrian civil war social media video archival projects.
I would hedge a bet, that you did not actually look up or (prior to today) follow this account. And that you confuse "apologia" with "serious concerns about fake 'evidence' from all sides, that muddles the debate and does a disservice to any realistic conversation about Israel's actions".
It's 2026, social media has to be flashy, go right to the gut. We've become dulled to the realities of the world, so harder hitting content is the only thing getting a reaction. And accounts/sites like this one provide that hard hitting gut punch, if need be by inventing a new narrative.
One can hold both thoughts at the same time and still understand, why a page like this causes concern.
Have followed them on twitter for a while, and the point is that this is an excuse to hide all the real evidence, by pointing out that some fake stuff might've gotten mixed in on the archival site which is just trying to do a good job. Parent commenters don't believe the genocide is real and try to play both sides. Absolutely revolting
I am a healthcare provider. Not only during SARS-CoV-2 have we been shat on, abused, misused, tossed into a lethal grinder, driven into suicide, driven into addiction, our personal lives and relationships destroyed. AND we don't get a month that's ours.
There's nothing wrong with having LGBTQIA+ flags in your app to highlight marginalized groups. But to respond to a plea for extension of that list with "fuck you, Nazi Transphobe Sexist Scum" isn't the way to go.
The VAST majority of my LGBTQIA+ friends in health care agree. Your candle won't burn brighter if you blow out other candles. Adding more colors, adding more flags, adding more recognition, does not diminish the recognition of the original marginalized groups. If anything, it creates understanding, community, personhood, and normalizes LGBTQIA+ as not an outlier but one in a scary number of identities and groups that are being mistreated.
I guess the author led with this to pad their critique, feeling that "we do scammy things with your referral links and we take cash in your name" wasn't enough.
Which says a lot more about them than it says about Brave.
Rescue treatments are symptomatic. Which makes a lot of sense, if you consider what (medically) constitutes "sepsis."
Any ED resident on their first week on the job should know how to diagnose sepsis: Temp >38°C (100.4°F) or <36°C (96.8°F), Heart rate >90, Respiratory rate >20 or PaCO₂ <32 mm Hg, WBC >12,000/mm³, <4,000/mm³, or >10% bands, Infection (suspected or present).
Double down on the blood work, take liquor, empirically give antibiotics (less and less useful, given resistances), drop temperature (paracetamol), add fluids (drops heart rate, ups blood pressure), wait for labs.
It's not hard, and I am so very sorry someone with sepsis signs was sent home. Sepsis is also a fast bastard. Meaning, from pathogen entering the blood stream to organ damage and conclusively death can be less than half an hour. That's the ones we can't catch. The guy with the ulcer, the person who injects things, the girl who didn't see a dentist about her developing abscess, the man who stopped his HIV meds... that's the ones I didn't in the past three weeks. I got them too late, or didn't see them until the ambulance unloaded a dead person.
Sepsis is a bitch. A total and utter bad player, something we drill into every resident from day one. Sometimes Mrs. Goodforall comes in with a light chest tightness and leaves on a hearse, sometimes Mr. Bluebird presents with nausea and crashes into a full on septic shock minutes later. Any one of those I can prevent, I will. I am, however, not God. Just a ED jockey with an infectious disease background. I'm probably the best hope my patients have, which isn't much, but it's something.
Thank you; yes, he had a clinical history of colitis and other stomach issues, and had visited the ER due to abdominal pain over a weekend. On Tuesday he collapsed at home and was gone. I don't know what transpired with the doctor (and didn't want to pry too much with the grieving family) but it sounds like it was just missed or his symptoms misunderstood. I heard grumblings that the doctor was at fault but I don't fault them - things just happen and while it is sad, it just happens.
If I understand correctly, this is one of those laws-of-exponents things that humans tend to have bad intuition for, right?
Bacteria growth, unchecked, is exponential. The only reason we stay a coherent organism at all in this crazy world of trillions of other organisms is that our immune system checks the hell out of bacteria growth.
... but when that's no longer possible, when the body goes from being a hostile growth environment to food... enterococcus faecalis has a doubling time of 18 minutes. One such cell, with completely-unchecked reproduction, would produce a number of itself to rival the cell-count of the entire body in only 10 hours, and it takes way less than 30 trillion enterococcus to kill a person.
When I went into residency, my attending once described any drug acting on reuptake (be it antagonistically, agonistic, or in a bifurcated model) as the medical equivalency of noticing your car is low on oil and, in response, pouring a few dozen liters of the stuff over the engine block.
Some gets to where it needs to be, the rest gunks up the engine on the outside and in places it shouldn't be.
Almost any drug acting on 5HT (fk acts on 2C), acts on other receptors as well. Fk acts on α1, M1-4, and many more, it's not very selective. A venerable bucket of oil, indeed. This is, what also causes Long-QT, feeding disorders, diarrhea, shorter pregnancies, dry mouth, sexual dysfunction, and more.
Sure, dropping such a bucket of oil can also, via inflammatory pathways, elicit IL-10 activation and, more importantly, act against hypertriglyceridemia. But that should not be sold as a solution to a problem. Again, to stay with contrived comparisons, if I load the boot of a car with C4, I am sure that some parts of the car will reach more than the car's stated maximum speed. But that's not a desirabe outcome.
As a last ditch, I'd consider it. But "preventatively" as suggested... that's a far, far, reach.
I get that fluoxetine, a relatively old SSRI is a dirty drug, but aren't newer serotonin modulators much cleaner? E.g., vilazodone, vortioxetine, and even old-fashioned Escitalopram (lexapro)?
My understanding is that escitalopram has pretty low binding affinity for other receptors than SERT.
But serotonin is active in many aspects of the body's physiology no? So just because it may not act on other classes of receptors, it still has wide ranging impacts. There are many kinds of SERT receptors, as they mentioned, Fk isn't all that selective about it
Fuck vilazadone and vortioxetine with 500kV. That shit gave me seizures, zaps, and myoclonus.
Fluoxetine made my mom murderously psychotic. Paroxetine gave me immediate serotonin syndrome.
The truth is most psychiatrists are unscientific shamans who don't measure or analyze the organ or systems they're supposedly treating.
The only thing I've found tolerable from more than a dozen medications has been mirtazapine. All SSRIs I've tried were of marginal benefit with terrible side-effects.
Sorry, what does this have to do with the study? Obviously reuptake inhibitors save many lives and you're acting like they're all unusable. As a doctor, isn't this irresponsible?
He says that a) yes there are many receptors which will be triggered by the same drug at the same time, so it can have a variety of effects, b) it's possibly not worth it to take it as a preventive measure. That doesn't mean he says it shouldn't be taken to cure or at least manage debilitating disorders like depression. Cost vs benefit.
The discussion of costs/risks of treatments is usually what's missing in the casual conversations about drugs. Ketamine or psylocybin are probably the best examples in the tech community, yes they can sometimes cure a depression, or at least suppress it for a while, but they can also cause psychosis (and other non-psychiatric symptoms), so they are used only after safer options fail.
Although I'm not sure I get the concern here, sepsis is very life threatening, so paying SNRI-level risk for prevention doesn't seem like an outright bad idea. Unless the idea would be for random people to start using this drug just in case they get stabbed and go septic - then I would say this is not a good idea. But I don't think this is what the paper describes.
That wasn't my takeaway at all. As someone who's been on the receiving end of various SSRIs for big chunks of my adult life their analogy seems pretty on-brand compared to the experience of taking SSRIs. They fuck with so many things that aren't the problem at hand it beggars belief. Anyway, if anything my takeaway was confirmation of my suspicion that SSRIs are the polar opposite of targeted therapeutics.
Usually they fuck with something like extra sweating or a little trouble sleeping. Severe side effects are very rare, they are widely used because they are so well tolerated. My own anecdote is: most elderly people should be on Cymbalta because they live in so much pain. I've been offered Prozac for chronic pain, I bet it would help them too. Boomers suffer needlessly. Get them on Prozac, please.
The point is that SSRIs (and reuptake inhibitors in general) are extremely crude. It's like using a dull rock instead of a scalpel, or full body radiation to remove a mole on your hand. They have a lot of secondary and tertiary effects we don't understand, nor do we truly understand the primary mechanism.
We don't know exactly what these drugs do to the body, how they do it, or what the consequences really are.
They have good outcomes for a small section of the population and that's about all we know.
One could argue that over-prescription of such a poorly understood class of drug is far more harmful.
After reading your comment, I was wondering "why do this study in the first place" if researchers are just pouring oil on an engine.
The last sentence basically says that it's too difficult to get new drugs approved, so instead let's try to find new benefits of already widespread drugs. I suppose it's better to pour oil on an engine than to have no oil at all.
> One of the most cost-effective and quickest strategies to develop treatment strategies is repurposing already approved drugs for new conditions. Our study provides sufficient rationale to further explore the therapeutic uses of SSRIs during infection and to reveal new and exciting immunometabolic targets during sepsis.
I think the analogy would work better if you had a couple of iron filings with the design of the engine block imprinted on it, then you constructed the engine by pouring buckets of stuff in the right proportions at the right time until the iron filings formed a working engine.
If such an engine existed, perhaps it might be more amenable to refilling its oil in such circumstances.
would have been interesting if they had constructed a temporal loading dose response curve which could support a prophylactic protocol for emergency or otherwise high risk hospital admissions.
By design, these effects are features, not bugs, when experienced by the mentally ill. It's a tangible, temporal mortification of the flesh beyond mere incarceration! Moreover, and effective deterrent against procreation, longevity, frugality, temprance, , and/or straying more than 5 minutes' Naruto Run from their own bathroom facilities.
It's considered immoral for Christians to sterilize themselves... but it's a civic virtue, and courageousness to feel oneself growing more impotent with successive phases of the Moon.
Matt, literally (he turned 21 then), came of age in the 2004-2006 Silicon Valley climate of the post-Bubble "Trümmerfrauen" (https://en.wikipedia.org/wiki/Tr%C3%BCmmerfrau) movements that brought us things such as DHH and Rails, Matt and WordPress, Andreessen being himself, and others, all of which are now considered "problematic."
I don't think Matt has changed. The climate these projects operate in, has. To some it's an eggshell walk, to others a game of signaling the right virtues while acting against them in secret, and to some a chance to achieve relevancy or dominance. And for all of them, there's a day of reckoning. 2005s proclivities have no similarities to 2025 dogma, and why should they. Neither did 2005 have any with 1985. Feel old, yet?
Matt's Matt. That Matt was what was needed to kick a floundering piece of software (P2) into the kind of trajectory that helped transform it into the absolute unit of a social and communications portfolio, Automattic is today.
That kind of Matt is a dinosaur in 2025. As were 1985 coders and founders in 2005. Heck, 2005 didn't look too kindly upon 1999 Silicon Valley mindsets.
I guess Matt's "problem" is not, that he has changed. Matt's difficulty is, that he hasn't, and that 2025 is nothing like 2005. And, like DHH or Andreessen or Brendan Eich back in 2014, that can ... hurt. I'm too old to care, but I'd presume today's "golden child" will be a very problematic person in 2045, unless they learn to change or hide behind signals.
Config being a programming language has insane advantages. Not only can I error check my config in vim or Visual Code, I can do insane things with logic that just don't work in other config file approaches. My laptop is connected to a 32" 4k monitor at work, standalone while traveling, and to a 27" 2k at home. WezTerm "knows" that, and sets things such as font size and line height automagically.
Even more, I can have split logic based on window size, window titles that show me who also checked out a file while I am inside an editor, even per-window color and font schemes.
All apps should use something like Lua for their config.
It's great that you (and many others) find it useful, but I genuinely have no idea what this is about. I switch my iTerm from my 13" MBP, 32" monitor, and iPad all the time, and I don't need any config to make it work. Maybe I just don't care enough about this stuff but I don't see what I would even configure this way.
Anyway, this is the reason I love the new wave of terminals, they bring new stuff on the table and anyone can find one they love. I just installed Ghostty and it works as I expect out of the box, with even less config (0) than I have on iTerm. And it's fast. Now I just hope they'll add a config UI some day (one of the reasons I prefer static config files: you can't really get a UI with a programming language) and I'll be in terminal heaven
If you don't care about this stuff you'll just as easily configure in a static key=value table whatever you like, lua doesn't limit you here. It's benefits are all optional
I've used wezterm for years and have never done anything fancy with the config, but this sounds awesome. I'd really appreciate it if you could link your config or a similar resource.
I just started using wezterm, my config isn't as mature or fancy, but I already found a spot where lua config is making me happy. I added a feature so I can command-click on Github PR numbers in Wezterm to take me to that PR on Github.com. Here's a permalink to the code: https://github.com/justjake/Dotfiles/blob/030c5d2b43e944df55...
The way this works in Wezterm is you can add regexes that match text in the terminal and format that text as links. So, I turn #(\d+) into "GITHUB_PR:$1" and then add a "on link clicked" callback to handle that special URL form by shelling out to `gh pr view --web $1` in the same working directory as the clicked pane.
This is what I love about wezterm. I have a whole system that detects lightness and changes themes automatically, and also sends commands down to any open nvim instances to switch colourschemes there.
The only downside is that there is no going back for me haha.
Lua is also simple enough that if you want to have a static config, you can have a single table that is very json-like.
Arc does some things right. Combining tabs and bookmarks into one cohesive display, that allows the moving of one to the other, makes sense. Having a floating command bar that does more than just "open this URL" as well.
Others have tried to solve the intersection of new discoveries and daily reading workflows, but only Arc seems to present the latter in a way that does not get in the way of the former and does not require N keypresses to get there.
Sidebar plus floating URL bar means much less window chrome, which is (especially for people like me who haven't owned a monitor or a desktop PC for a decade) a welcome freeing experience that maximizes screen estate.
Having a baked in tracker stripper for a one-keypress URL copy is, especially for people like me who copy dozens of URL daily, a boon. No other browser seems to think, that this is something that is needed. And most users seem to have arranged themselves with two keystrokes to highlight the URL bar and copying the contents, followed by dozens of deletes to remove trackers.
Sure, it's small stuff and easily waved off, but if none of the other browsers wants to break with the Netscape early days paradigms, Arc it is[1].
[1] Zen Browser tries, but then, that Mozilla underpinning often sabotages the experience.
> Combining tabs and bookmarks into one cohesive display
I've tried to experiment with different ways to present browsing information. One approach is to present the tabs, bookmarks, and history on one open cohesive page, and allows searching all of them at once. Of course the devils are in the details, how to effectively navigate to different sections of the page, how to make sure performance is good, etc. I made a browser extension to try out the idea [1].
> Combining tabs and bookmarks into one cohesive display, that allows the moving of one to the other
While I haven't used arc and don't have experience how that feature feels, I think the over 20 year old concept of a bookmarks menu, and tabs, as separate things is the best and never needed solving, and any attempt be different is worse than the original (like android firefox and its 'collections'. Why? Or Linux file managers hiding bookmarks different locations that operate differently called "Go", "Places" and actual "Bookmarks" that change through versions and sometimes coexist for some reason so you never know which menu it's going to be this time)
Nowhere on their site (that I can find) do they mention that. There's lots of sales talk about it does all the work and adapts, etc., but nothing about what it actually does.
I can't see a reason to change browsers. What are the features that Arc has that other browsers don't have?
Their sales pitch is the problem they need to solve.
Firefox also has a "Copy without URL tracking" option in the URL bar context menu. It's not one-keypress, but clearly a tracker stripper is not Arc-exclusive.
Also no idea what you are talking about with Zen's "Mozilla underpinning sabotaging the experience".
Unfortunately not. There are dozens of companies reselling "old" Libre 2 sensors for "fitness and health" applications. BG has joined HRV and other semi-bogus metrics as one of the numbers that drive a whole subculture of health data.
To correct this, though. You can buy all those in the US as well. Holter and FirstBeat are selling clinically validated and FDA approved mutli-lead ECG, Derxcom is selling an over the counter CGM, as is Abbott with the Libre 2, and a Chinese company has recently joined there, too.
Low calorie meal replacements are all over the store, too.
If you're a member of this orthorexia/orthovivia crowd, you have the same access to tools as you do in the EU, often more so.
The lack of a hypo alarm is the reason the Stelo is not past FDA, yet.
Luckily, there's xDrip4iOS and xDrip++, not to mention Suggah and others, who will happily do the alarming part for you. Not to mention, that to many of us T1D, the CGM is just a secondary data point for our loop, which has a CGM already built in.
I beliebe xdrip is not (yet) steel compatible. Also interesting to see if this thing really sends data only every 15mins or is it done in the app. 15min is way too much for looping.
I am not a fan of domain name cessation or any kind of blocking access to data, but I'd imagine NameCheap did have a particularly high amount of complaints and legal inquiries (one comes to mind, where the site posted pictures of a Hamas hostage in a tunnel as "Israel starves teacher and forces him to dig his own grave" that is in litigation), that at some point beg the question if $5/year is worth it.