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SSRIs and SNRIs just didn't work very well for me. If they had an positive effect at all, it wasn't enough to rise above the proverbial noise.

Coming off of them wasn't too bad though. I got the brain zaps, but those were easy to cope with.

More than anything the whole experience was a waste of money, and what finally fixed my problems was retirement and a greater attention to my health.


Have you looked into mirtazapine (tetra cyclic), vortioxetine (serotonin modulator) or atomoxetine (SNDRI). Atomoxetine has been a god send for me.

I stopped looking into drugs when I stopped having problems.

Atomoxetine can cause some wild mood-related side effects, just as an FYI for anyone considering it. For me, it made me perpetually pissed off, and made me feel like I had a cold. I’m jealous of people it works well for though - seems like a great drug when it works!

I've tried 20-some-odd antidepressants titrating off and on and usually back off again.

Mirtazapene (ATeCA) is the only one that could manage my depression. Unfortunately, it leads to severe weight gain that my health plan's formulary refuses to cover GLP-1 for because obesity is considered "a choice". It's the only one where the depression mostly goes away and the side-effects aren't life-threatening/-debilitating for me. If I forget a single dose at night or anytime I go to sleep without taking it first, I end up with almost exactly the feeling of an alcohol hangover. It's also a pretty powerful antihistamine. I also usually can't get to sleep if I don't take it. :/

Vortioxetine gave me horrific myoclonus and vestibular symptoms.

Atomoxetine is mostly for ADHD and gave me tachycardia, profuse sweating, uncomfortable nervousness, and anxiety. It didn't do shit for my ADHD or depression.

YMMV.


They work so well for some they are miracle drugs, and for others they do nothing or have negative effects. This is typical. We still don’t fully understand why or even why they work at all.

The problem is one of the alternatives they consider worse than homelessness is a life without opioids.

I had cousin who was homeless in San Diego. Over the years she came into money a couple times, either from family members or through inheritance. Instead of getting a place to live she figured drugs were a better use for that money. We tried everything to get her off the street, and nothing worked. She wouldn't even stay at a shelter. Because she had no intention of giving up the drugs.


You don't go to jail for possession of weed in most US states. You won't even go to jail for dealing unless you've been busted multiple times or you're moving heavy weight.

When you see statistics about people incarcerated on marijuana charges, what they normally obscure is either that's not the only charge or they pled down from something more serious.

There isn't a single person in federal custody there for marijuana possession and only that.


Most Asian countries are pretty serious about keeping drugs out of their countries. In Japan's case it's a little easier since they're an island nation.

You can get a life sentence there for first offense import or manufacture of narcotics. Beyond that, your family will suffer socially.


I'm a bit mystified why anyone would bring an electronic device over an international border with anything that could be construed, fairly or not, as evidence of criminal behavior.

The last time I tried to do that on a trip to Germany, admittedly many years ago, I found I could not get phone service without a local address.

They can hold you for a few hours while they investigate, but they can't just arbitrarily detain you without a legal basis.

I wouldn't assume that to be the case. It's illegal under federal law to destroy evidence of a crime. Just what the government needs to do to show that you've destroyed evidence of a crime and not just the sexting you did with your girlfriend is a pretty murky area of law, from what I can tell.

I would not present a phone to customs that had clearly just been wiped.


You're speaking nonsense since there was no charge or warrant against him. There was no crime that was committed. People are free to use their phone for f sake. People who reason as poorly as you will lead to all remaining rights being lost.

The way he wiped it is legal for the same reason. It was an illegal search and he was under no obligation to preserve the data on his phone.

It's legal to refuse to provide a PIN/password in the US. He's a US citizen so they couldn't refuse him entry. If he wasn't then the result would be getting deported.

It likely would have been a much better decision to refuse to provide the PIN/password and rely on the encryption and device security instead. He could have done a reboot or shutdown in advance but even without that it would have done it automatically via the locked device auto-reboot timer. The secure element only allows 20 attempts for key derivation with rapidly growing delays between those. If he had a strong passphrase then even a secure element exploit wouldn't obtain the data protected by it.


Ah, I see where you've gone wrong. You're expecting to apply common sense and reason to the law.

That kind of thinking has landed a whole lot of people in prison.


You're losing track of the discussion which was about erasing data before arriving at the counter. In any event, if you're so willing to "bend over" to the man, please try not to take others down with you.

I did not, in fact, lose track of that point. I was merely pointing out it's not a solution. I'm sure the guy in the topic article thought he had things figured out, too.

You know how they say ignorance of the law is no excuse? That holds true even if the law seems unreasonable or incomprehensible.


>Much of this happens in agricultural settings, where any work done by children under 12 is counted as child labor, even if it is light and non-hazardous.

>Imagine an 11-year-old helping on a family farm in sub-Saharan Africa. He feeds the animals every day, a couple of hours in the morning and again in the afternoon.

...

>As I mentioned above, the reason this type of work counts as child labor under the international conventions is that it’s considered to be harmful because of what it displaces: the children’s time for studying, resting, playing, and socializing.

This seems overly broad. I don't think it's unreasonable to have younger children doing chores, and the definition they've adopted includes children doing anything economically productive for even one hour a week. Yes, a couple hours twice a day is too much, but I don't think having your kid feed the animals for 45 minutes before school is going to stunt his or her development.


It's really difficult to see what technologies will be enablers of state power. IMO, the techs ushering in 1984-levels of control are wifi, cheap cameras, and LLMs. The three technologies on their own are beneficial, but taken together they're going to make Big Brother seem impotent.

Hard disagree. Plenty of new technologies have readily apparent straight-forward application for government use.

You're arguing your point by naming a technology that speculative fiction regularly foresees advancements in, and loves using in stories as the enabler of more intrusive state power.

More surveillance records, better processing and recall of those records are like THE THING when it comes to more law enforcement and passive coercion by the state.

There is honest to goodness disruptive tech that takes time for society to adapt to and reveal where state power wants to go. But those are the vast minority. I think it's a pasttime of industry to play ignorant to how their products will interplay with the government's obvious motivations.


I think of it as, we've had a hurdle where computers were too slow to organize the data humans produced, but have since crossed it. LLMs and CV also enable analysis of fuzzy data, which hasn't been possible before. This makes me uneasy, to say the least.

I asked Claude to analyze and datamine all of my eleven thousand HN comments, plus my reddit comments, lobsters comments, mailing list emails, stackexchange content, etc. With this database it managed to create an entire dossier about me. It could psychologically profile me, and it had a better and more complete view of me than my literal psychologist. We identified things like weaknesses, social engineering susceptibility, likely scenarios. It got to the point it started digging into open source projects I made when I was a teenager and started making eerily accurate inferences about my childhood.

I can't even imagine what the NSAs and CIAs of the world are capable of with their limitless black budgets. Anthropic only balked at domestic surveillance, it had zero objections towards allowing the US government to surveil foreign persons like me.


I completely agree. I've done a similar experiment on this rather young HN account and it was already able to deduce some things that I never explicitly stated. It probably doesn't require much more than a megabyte of someone's Slack messages or emails to build a profile on them, and there's much more data out there than that. People can be linked by their footprints in big tech products, or more crudely by techniques like stylometry, which is fully accessible to foreign governments. LLMs will likely enable even more aggressive techniques for linking people's public data, let alone to analyze it.

Precisely, modern multimodal LLMs are a breakthrough in ultra high volume data processing, for all their flaws

And drones.

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