> When practitioners say "PCR" they don't (usually) just mean amplifying DNA for use as part of the input to another process.
I definitely do.
> What they usually mean is PCR with chemistry that selectively amplifies some specific sequence of DNA. This chemistry has dyes in it which fluoresce when illuminated at some specific wavelengt
This is called qPCR (and qRT-PCR, and RT-PCR and ‘Taqman assay’... But it's not called PCR because it's not just PCR).. It has uses outside of diagnostics (which is what it seems you're most familiar with).
"Good for fever"? Only ignorant consumers would attempt to counteract the body's very own defenses against infection and disease.
A fever is not dangerous within normal parameters, except for being dangerous to the virus and bacteria that threaten the body. Your body runs a fever because it engages in a battle to the death with these microbes.
If you defeat the body's own defenses by lowering the fever, for example if you are a nervous mother who hates her baby's fussing, or if you're hospitalized and the nurses are laser-focused on "number go down" treatments, then you can expect to be ravaged by the contagion for much longer than expected.
The priorities have drifted. In the middle of night I don't care about getting healthy, I need to get rid of fever, so I can fall asleep and able to got to work/school in the morning. And somehow there is never right time to be sick and everyone just want to supress syndromes here and now.
Someone with a basic understanding of evolution and biology understands that evolution will take any free lunch it can get.
The vast majority of the time medicine can only ever help with (acute) symptoms and rarely the underlying cause unless it is something like vaccines or antibiotics.
Medicine has side effects because if there was a free lunch to be obtained from medicine, the human body would have synthesized the medicine directly. Hence medicine is always about making tradeoffs.
When it comes to general health, there is always a causal chain of cause -> primary symptom -> secondary symptom -> tertiary symptom -> ... and a lot of medicine tends to work on the secondary or tertiary symptom.
Pain evolved to be an accurate indicator of damage to encourage you to stop ruining your body and not a punishment.
I am forever astounded by the self-satisfaction of programmers as they talk about domains unfamiliar to them.
Just imagine someone trying to lecture a network engineer about how really async bugs should really never be different than bugs you see single-threaded if you use a semaphore. I mean, that's why we have semaphores!
Anyway, the temperatures attained during fevers are at best bacteriostatic (read not helpful in actually treating an infection that would lead you to seek medical care). If you've got evidence-based arguments, happy to counter them. Just please don't evoke 'evolution' to explain your bias-du-jour.
Evolution didn't create the personal computer or build a skyscraper. We're firmly in uncharted territory wrt things our bodies were evolved to deal with. As a great example, human temperature has been going down over time—evolution tells us that must mean we're all more susceptible to getting sick!!! https://med.stanford.edu/news/all-news/2020/01/human-body-te...
This is a good argument, but it has a flaw here, which is that a systemic fever during illness may still be an evolutionarily beneficial adaption on average if there are a some situations where it can be the difference between life and death, e.g. bacterial pneumonia or sepsis, but that doesn't mean it's equally useful for all types of illness.
I did a fevered research dive last time I had the flu and came to the conclusion that there wasn't really any good evidence that fever is helpful for flu, and I should have few compunctions about suppressing it. (And that most of the situations where fever is really valuable for are ones where in the modern world you should go to a hospital and in the case of a bacterial infection be given antibiotics)
> It's estimated that between $250 billion and 500 billion is laundered through US banks every year, though some portion of that is via correspondent banking and not just individual account money muleing.
The money laundering is not happening through consumer deposit accounts (I've never heard your term money mueling and it's almost definitely not people moving $10,000 at a time if that's what you are suggesting).
It is wanton disingenuity to think that the goal of this rule is prevention of money laundering.
I didn't say that was the goal. I explicitly said that it wouldn't do anything about it. Just that it happens.
And absolutely it happens, particularly with networks of accounts connected to China. Just because you've never heard of it doesn't mean that it doesn't happen. FinCEN has been publicly chasing this down for years. Although hawala networks are also a big source of that not mainly personal banking.
Also you're missing the forest for the trees here. Money laundering will most often happen through business bank accounts but a large number of business account holders also have personal accounts at the same bank and link them out of convenience.
Personal ID is also required to open a business bank account. This requirement will likely apply to those as well.
> Also you're missing the forest for the trees here
I see what you're saying - I am just trying to convey that the $250 billion dollars being laundered is commercial. It's hard to imagine how anyone can come close to those figures by using consumer accounts, linked or not.
I definitely do.
> What they usually mean is PCR with chemistry that selectively amplifies some specific sequence of DNA. This chemistry has dyes in it which fluoresce when illuminated at some specific wavelengt
This is called qPCR (and qRT-PCR, and RT-PCR and ‘Taqman assay’... But it's not called PCR because it's not just PCR).. It has uses outside of diagnostics (which is what it seems you're most familiar with).
Either way, the article is not about qPCR.
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