“ what we believe, what I believe is as we move from a pandemic state, from a pandemic situation to an endemic situation, normal market forces, normal market conditions will start to kick in. And factors like efficacy, booster ability, clinical utility will basically become very important, and we view that as, quite frankly, a significant opportunity for our vaccine from a demand perspective, from a pricing perspective, given the clinical profile of our vaccine. So clearly, more to come here. But we think as this shifts from pandemic to endemic, we think there's an opportunity here for us.”
“ When we started building Stack Overflow in 2008, we didn’t have that choice. There was no Docker (2013), no Kubernetes (2014). Cloud computing was in its infancy: Azure had just launched (2008), and Amazon Web Services was about two years old. What we built was designed for specific hardware and made a lot of assumptions about it.”
Problem with this: keep your phone with you always conflicts with don’t have secure conversations within mic range of your phone. You can’t do both of these.
But otherwise this is great and I would probably add “reset and replace devices often.”
Are lockers really that secure? Similar documents advise against leaving laptops in hotel rooms or cars, even if locked, because they are easy to get into. I imagine a locker is not hard to break into. Small locks can be picked in a second or two by people with practice, which does not look different than retrieving your own phone.
The lockers are just so you have a place to put your phone. They are not secure in any way. Using a keyed locker just ensures you don't pick up someone else's phone by accident after the meeting. Remember that secure rooms live inside secure buildings, usually inside a secure facility with a fence and guy standing at the gate. And the guy has a gun.
“ vCJD or “classic” CJD, which is not known to be caused by prions from animals. Classic CJD strikes an estimated one person per million. Some 80% of cases are sporadic, meaning they have no known cause, ”
Who knows really. 10 years is a long time to wait and worry, but it can take up to 50 years to express itself. Just imagine spending your whole life worrying about this.
Bear in mind that eating muscle tissue from infected animals is a much lower risk than innoculating yourself directly with brain matter from an infected animal.
The prion protein is expressed in the central nervous system, which isn't legal for human consumption. Also, ingestion of meat exposes it to stomach acid and digestive enzymes before it gets into the consumer's circulation -- enzymes that break down foreign proteins into (harmless) amino acids.
In contrast, accidentally injecting yourself with material from an infected brain is about the most direct possible infection route.
All sales of beef on the bone was banned too. Even Bovril had to change their recipe for a few years.
The ban was introduced on December 16, 1997, after government advisers reported small risks that small nerve endings near beef bones and bone marrow might be infective. The ban included cuts such rib roasts and oxtail, as well as soups and stock cubes made in Britain from beef bones.
The ban was lifted Tue 29 Nov 1999, but other bans on using as food more risky parts of cattle - brain, eyes, tonsils, spinal cord, spleen and intestines - remained in force, as did ban on use of bones in manufactured food and cattle more than 30 months old are banned from the food chain.
Things have been eased further since 1999 but I'm not sure we can get brain on the menu in the UK...
Mammalian proteins don’t differ from each other all that much so it makes sense the prions of any other mammal could potentially infect humans. Though the further away in the evolutionary tree the less likely I imagine.
Sometimes when I’m dumber than usual I try to make up for it with more coffee. Wonder if something like that could be driving this. People with dementia try to compensate with more coffee.
https://s21.q4cdn.com/317678438/files/doc_downloads/Transcri...
“ what we believe, what I believe is as we move from a pandemic state, from a pandemic situation to an endemic situation, normal market forces, normal market conditions will start to kick in. And factors like efficacy, booster ability, clinical utility will basically become very important, and we view that as, quite frankly, a significant opportunity for our vaccine from a demand perspective, from a pricing perspective, given the clinical profile of our vaccine. So clearly, more to come here. But we think as this shifts from pandemic to endemic, we think there's an opportunity here for us.”