There is another active study with a device called the DidgeriTU. Which is a mouth breathing appliance that you blow in. But fits in the palm of your hand. I'm interested to see the results of that one!
I'm actually trying this right now for my moderate sleep apnea.
I had an AHI of 17 a few years ago and then I had deviated septum surgery and taught myself how to breathe through my mouth using mouth tape.
And had a love-hate relationship with CPAP and finally got consistent with it in the past year.
And now I found a new sleep medicine doctor who agreed to help me try out this claim in the study. (Previous sleep doctor had no interest in helping me with that).
So we took another sleep test and AHI is still about 17. I'm doing the didgeridoo for 3 months for 15 minutes a day, using the air didge, which is adjustable but I'm using it in the lowest tone which is A.
And we are going to test again after the 3 months is up!
Many people say that until they almost die. 350,000 people died of heart attacks in the US in 2025. A very preventable situation. Many more almost died. In many of those said they'd rather be dead than not eat butter, red meat and cheese.
In their new study, published in Science Advances, they describe how they mapped the DMT biosynthetic pathway and engineered a type of tobacco plant to produce five different natural psychedelics.
It only reduces by 4 events per hour. That seems like it might be helpful for someone with mild sleep apnea. But not with moderate or severe sleep apnea.
Adult AHI Severity Levels
Normal: Less than (5) events per hour.
Mild Sleep Apnea: (5) to (14.9) events per hour (frequent minor interruptions).
Moderate Sleep Apnea: (15) to (29.9) events per hour.Severe Sleep Apnea: (30) or more events per hour.
"By mapping the neural circuits that lead to this common condition, work from the Horner lab laid the foundation for AD109, a new treatment developed by researchers in Boston to specifically target the two pathways that contribute to sleep apnea. The daily oral medication contains two drugs: one that increases noradrenaline levels and another that blocks muscarinic receptors.
In a recently published phase 3 randomized clinical trial, people with mild to severe sleep apnea who received AD109 had less airway obstruction and higher oxygen levels than those who received a placebo. On average, per hour of sleep, participants on AD109 had four fewer events where they stopped breathing or had very shallow breathing."
They say later in the article that the pill is a good option for folks that can't or won't use the CPAP.
A CPAP is really effective, so it would be first line treatment. If I couldn't use one but needed it, I'd be happy to have fewer events per hour than all of it. Improvement is better than nothing in this case. Besides, a lot of drugs are improved after the initial breakthrough drug - so this gives hope that we might actually be able to be free of the CPAP for many more folks.
CPAP reduces my AHI from 55-60 down to less than 0.5. For people with severe sleep apnea, an 'improvement' of 4 events per hour does absolutely nothing for their health and provides a false sense of security. Their time, money, and energy is much better spent learning how to adapt to CPAP.
Oof, and here I thought my AHI of 69 was bad (which it kind of is regardless). My condolences. Glad the CPAP helped, it completely and utterly changed my life too.
the cpap is a wonder, I can't sleep without it. I only wish I'd gotten one 10 years sooner. I have whole years of my life missing from my memory - REM sleep is very important to long-term memory formation.
Ouch! I'm under 3. It follows me everywhere too. Early on, I kept trying leave without it when sleeping out for one night. All it achieved was having to catch up on sleep for the next few days. Nowadays I use it even when taking a short nap.
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